##跨越2100公里，广东脐血为极早发型炎症性肠病患儿带来新生
中新网广州8月21日电 (记者 蔡敏婕) 7个月大的花花(化名)被确诊为极早发型炎症性肠病，这是一种罕见且严重的疾病，给孩子带来了发热、肺炎、腹泻、口腔溃疡、便血等多种症状，更严重的是影响了她的生长发育。面对困境，医疗团队决定为花花进行造血干细胞移植，而这份“救命血”来自2100公里外的广东省脐血库。
据了解，极早发型炎症性肠病患者除了常见的肠道症状外，还会导致免疫缺陷。花花由于肠道消化吸收不好，体重严重不足，仅有5.4公斤，属于严重营养不良。为了帮助花花对抗肺炎，提高她的抵抗力，医生团队为她寻找合适的造血干细胞供者。
幸运的是，广东省脐血库查询到一份符合花花血型且符合临床使用需求的脐血，这份脐血采集于2020年6月12日，来自惠州市中心人民医院。为了确保这份“生命火种”能准时送到花花身边，广东省脐血库护送人员决定提前动身，将脐血空运至北京。
6月28日，花花在北京京都儿童医院接受脐血回输。随着粒细胞和血小板的植入，花花精神状态良好，并顺利出院。8月21日，花花回到医院复诊，结果显示身体各项指标均恢复良好。
北京京都儿童医院特需住院部副主任陈姣表示，选择脐血造血干细胞移植有两个优势：一是脐血是实物保存，检测合格便能随时出库；二是脐血一旦植入成功后，后期慢性排异风险小，孩子可以有更好的生存质量。
陈姣还强调，未来自体脐血的用途会越来越广泛。经济条件许可的家庭可以考虑储存脐血，也可以选择捐献。这样脐血库就会越来越充盈，医生们在临床中治疗，找到合适的脐血越来越容易，可以拯救更多人的生命。
截至今年7月31日，广东省脐血库已出库5086份脐血，救助3794位不同疾病的患者。花花的故事再次证明了脐血造血干细胞移植在治疗儿童原发免疫缺陷病方面的积极作用，也为更多患病儿童带来了生的希望。
英语如下：
##Across 2,100 Kilometers, Cord Blood Saves 7-Month-Old Infant with Early-Onset Inflammatory Bowel Disease
**Keywords:** Cord blood, inflammatory bowel disease, transplantation
**News Content:**
A 7-month-old girl named “Hua Hua” (pseudonym) was diagnosed with very early-onset inflammatory bowel disease (VEOIBD), a rare and severe condition that caused her to experience fever, pneumonia, diarrhea, oral ulcers, and rectal bleeding. The disease also severely impacted her growth and development. Faced with this challenge, the medical team decided to perform a hematopoietic stem cell transplant for Hua Hua, and the “life-saving blood” camefrom the Guangdong Provincial Cord Blood Bank, 2,100 kilometers away.
VEOIBD patients, in addition to common intestinal symptoms, also experience immune deficiencies. Hua Hua, due to poor intestinal absorption, suffered from severemalnutrition, weighing only 5.4 kilograms. To help her fight pneumonia and boost her immunity, the medical team searched for a suitable hematopoietic stem cell donor.
Fortunately, the Guangdong Provincial Cord Blood Bank found a cord blood unit that matched Hua Hua’s blood type and met clinical requirements. This cord blood unitwas collected on June 12, 2020, from Huizhou Central People’s Hospital. To ensure this “life spark” reached Hua Hua on time, the Guangdong Provincial Cord Blood Bank’s escort team decided to leave early and air transport the cord blood to Beijing.
On June 28, Hua Hua received the cord blood transfusion at Beijing Children’s Hospital. With the implantation of neutrophils and platelets, Hua Hua’s mental state improved, and she was discharged smoothly. On August 21, Hua Hua returned to the hospital for a follow-up visit, and the results showed that all herphysical indicators had recovered well.
Chen Jiao, Deputy Director of the Special Needs Ward at Beijing Children’s Hospital, stated that choosing cord blood hematopoietic stem cell transplantation has two advantages: firstly, cord blood is physically preserved, and once tested and qualified, it can be released from the bank at any time; secondly, once cord blood is successfully implanted, the risk of chronic rejection is low, allowing the child to have a better quality of life.
Chen Jiao also emphasized that the future applications of autologous cord blood will become increasingly extensive. Families with the financial means can consider storing cord blood or choosing to donate it. This willenrich the cord blood bank, making it easier for doctors to find suitable cord blood during clinical treatment, saving more lives.
As of July 31, 2023, the Guangdong Provincial Cord Blood Bank has released 5,086 cord blood units, helping 3,794 patientswith various diseases. Hua Hua’s story once again demonstrates the positive role of cord blood hematopoietic stem cell transplantation in treating primary immunodeficiency diseases in children, bringing hope for life to more children suffering from these diseases.
【来源】http://www.chinanews.com/sh/2024/08-21/10272655.shtml
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